Newsletter looks like what I may need.
However can I ask –
I have subscribers who live all over the place and sometimes I need to send out information relating to events that are happening in a particular location.
Similarly I have subscribers who are interested in particular sorts of events and not others.
Is it passible to select subscribers from the list according to there contents of particular fields?
If you axctivate the user preferences in the subscription form panel, users can selet their preferences and you can use them to target the recipients. Try it, if your needs are more complicated let me know!